PENGARUH WAKTU INKUBASI TERHADAP DIAMETER ZONA HAMBAT ANTIBIOTIK PADA UJI SENSITIVITAS BAKTERI KLEBSIELLA PNEUMONIA
DOI:
https://doi.org/10.33992/meditory.v11i1.2361Keywords:
Keywords, Inhibition zone diameter, incubation time, sensitivity testAbstract
Background: Several analytical factors can affect the diameter of the inhibition zone; This factor must beinvestigated toguarantee thevalidityofthe sensitivitytestresults. Aims: This study was to determine the pattern of influence of variations in incubation time on thediameterofthe antibiotic inhibition zone in the sensitivity test of Klebsiella pneumoniae. Methode: this research is a pre experimental design with a Static Group Comparison design.The diameter of the antibiotic inhibition zone with variations in incubation time was measured and analyzeddescriptively.The results: The diameter of the inhibition zone on the variation of the incubation time showed a patternof the influence of the incubation time on the diameter of the antibiotic inhibition zone in the bacterialsensitivity test, namely at 6-18 hours, an increase in the diameter of the inhibition zone and 18-48 hours a decrease in the diameter of the zone. Inhibite ach antibiotic. Conclucion:This study concludes that the reisasignificant effect with the pattern of theinitial incubation time(6-18hours) affecting the broader or larger diameter of the inhibition zone and the subsequent incubation time of 18-48 hours decreasing the diameter of the inhibition.
Keywords: Inhibition zone diameter, incubation time, sensitivity test
References
Warganegara E, Apriliana E, Ardiansyah R. Identifikasi Bakteri Penyebab Infeksi Luka Operasi ( ILO ) Nosokomial Pada Ruang Rawat Inap Bedah dan Kebidanan RSAM di Bandar Lampung. Pros SNSMAIP III. 2012;(978-602-98559-1–3):344–8.
Tarina NTI, Kusuma SAF. Deteksi Bakteri Klebsiella pneumonia. J Farmaka. 2017;15(2):119–26.
Konoralma K. Identifikasi Bakteri Penyebab Infeksi Nosokomial Di Rumah Sakit Umum GMIM Pancaran Kasih Manado. 2019;8(1):23–35.
Kemenkes. Profil Kesehatan Indonesia Tahun 2019. Short Textbook of Preventive and Social Medicine. jakarta: Jaypee Brothers Medical Publishers (P) Ltd.; 2020. 28–28 p.
Mazzariol A, Bazaj A, Cornaglia G. Multi-drug-resistant Gram-negative bacteria causing urinary tract infections: a review. J Chemother. 2017;29:2–9.
Khusuma A, Safitri Y, Yuniarni A, Rizki K. Uji Teknik Difusi Menggunakan Kertas Saring Media Tampung Antibiotik dengan Escherichia Coli Sebagai Bakteri Uji. J Kesehat Prima. 2019;13(2):151.
Soleha TU. Uji Kepekaan Terhadap Antibiotik. Vol. 5, Juke Unila. 2015. p. 121.
Carrol KC, Hobden JA, Miller S, Morse SA, Mietzner TA, Detrick B, et al. Mikrobiologi Kedokteran Jawetz, Melnick & Adelberg Ed 27. 27th ed. Allen, Handoko C, Agustina L, Hariyanto RB, Sadikin RE, Agustin S, et al., editors. jakarta: penerbit buku kedokteran EGC; 2017. 914 p.
Brooks GF, Carrol KC, Butel JS, Morse SA, Mietzner TA. Medical Microbiology. 26th ed. Principles and Practice of Pediatric Infectious Diseases. Elsevier; 2013. 690-692.e1 p.
van den Bijllaardt W, Buiting AG, Mouton JW, Muller AE. Shortening the incubation time for antimicrobial susceptibility testing by disk diffusion for Enterobacteriaceae: How short can it be and are the results accurate? Int J Antimicrob Agents. 2017;49(5):631–7.
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