HASIL PEMERIKSAAN IMUNOKROMATOGRAFI COACTAIL ANTIGEN M.TUBERCULOSIS DAN METODE MOLEKULER PADA SUSPEK HIV

Rizana Fajrunni'mah

Abstract


Background Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (MTB) infection. Tuberculosis is one of the most common infections in people with HIV/ AIDS. Deaths due to TB in HIV patients occur due to delayed diagnosis. GeneXpert is a breakthrough discovery for TB diagnosis based on molecular examination using the semi quantitative Real Time Polymerase Chain Reaction Assay (RT-PCR) method. An examination has now been developed to detect MTB antigens using the method of rapid immunochromatography in the hope that it can be used as a means of supporting TB diagnosis better than detection of antibodies to MTB.

Aim This study aims to compare the results of the TB GeneXpert RTPCR method with the rapid immunochromatography method in suspect HIV.

Method This study uses a quantitative design with observational analytic design (cross sectional) with primary and secondary data collection.

Result The results of this study found the value of sensitivity, specificity, accuracy, positive predictive value, negative predictive value of the ICT test in a row of 21%, 76%, 40%, 55.8%.

Conclusion ICT TB has low sensitivity and sufficient specificity so that it is still not good if used for initial screening to detect pulmonary TB in suspect HIV.

 


Keywords


Tuberculosis, HIV, moleculer method, rapid immunochromatography method

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DOI: https://doi.org/10.33992/m.v8i1.1093

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