PEMERIKSAAN KLINIK BERBASIS BIOSENSOR BAGIAN 2: Biosensor Virus Untuk Deteksi Penyakit Patogen

NUR HABIBAH

doi:10.33992/m.v4i2.54

Authors

NUR HABIBAH Politeknik Kesehatan Denpasar, Jurusan Analis Kesehatan, Indonesia

DOI:

https://doi.org/10.33992/m.v4i2.54

Abstract

Nowadays, rapid determination of several viruses which caused pathogen diseases is really important. Most of rapid detection of human pathogen viruses was developed by using biosensor technology. Biosensor technology offers several advantages, such as simple, efficient, low cost, fast response, easy to operate, and reliable. Viral detection by using biosensor can also avoid the delay of diagnosis, so the doctor can determine the type of drugs quickly and also can decide the type of patient care, properly. Most of biosensor for virus detection was exploited by using electrochemical principle, with amperometric and volumetric transducer. Almost of virus biosensor used immobilized antibody onto electrode surface as a biorecognition element. Some of viruses that could be detected by using electrochemical biosensor are HCV, HBV, HIV and influenza virus. However, quality control of the biosensor result is important, so the biosensor could be selected as an alternative method for on-site determination, especially in clinical determination. Keywords: biosensor, virus biosensor, virus detection, pathogen diseases detection

References

E.B. Bahadir and M.K. SezgintÃ¼rk, Applications of Commercial Biosensors in Clinical, Food, Environmental, and Biothreat/Biowarfare Analyses, Anal. Biochem., 2015 (478), 107â€“120.

V. Perumal and U. Hashim, Advances In Biosensors: Principle, Architecture And Applications, J. of App. Biomed. 2014 (12), 1â€“15.

Caygill, R.L., Blair, G.E. and Miller, P.A., A Review on Viral Biosensor to Detect Human Pathogens, Anal. Chim. Acta, 2010 (681), 8-15.

Yadav, R., Dwivedi, S., Kumar, S. and Chaudhury, Trends and Perspectives of Biosensors for Food and Environmental Virology, Food Environ. Virol, 2010 (2), 53-63.

Altintas, Z., Gittens, M., Pocock, J. and Tothill, I.E., Biosensor for Waterborne Viruses: Detection and Removal, Biochimie, 2015 (115), 144-154.

Yang, L. and Bashir, R., Electrical/electrochemical impedance for rapid detection of foodborne pathogenic bacteria, Biotechnol. Adv., 2008 (26), 135â€“150.

Ricci, F., Volpe, G., Micheli, L. and Palleschi, G., Anal. Chim. Acta, 2007 (605).

Munoz-Berbel, X., Godino, N., Laczka, O., Baldrich, E., Munoz, F.X. and Del-Campo, F.J., Impedance-Based Bioensors for Pathogen Detection, Springer, 2008.

Wark, A.W., Lee, J., Kim, S., Faisal, S.N. and Lee, H.J., Bioaffinity Detection of Pathogen on Srfaces, J. Ind. Eng. Chem., 2010 (16), 169-177.

Malhotra, B. D., Chaubey, A. and Singh, S.P., Prosepect of Cnducting Polymers in Biosensors, Anal. Chim. Acta, 2006 (578), 59-74.

Singh, R., Mukherjee, M.D., Sumana, G., Gupta, R.K., Sood, A. and Malhotra, B.D., Biosensors for Pathogen Detection: A Smart Approach Towards Clinical Diagnosis, Sens. And Act. B: Chem., 2014 (197), 385-404.

Drummond, T.G., Hill, M.G. and Barton, J.K, Electrochemical DNA Sensors, Nat. Biotechnol., 2003 (21), 1192-1199.

Mothershed, E.A. and Whitney, A.M., Nucleic Acid-Based Methods for the Detection of Bacterial Pathogens: Present and Future Considerations for the Clinical Laboratory, Clin. Cim. Acta, 2006 (363), 206-220.

Girousi, S., Karastogianni, S. and Serpi, C., Innovative Configurations of Electrochemical DNA Biosensors (A Review), Sens. Electroanal., 2011 (6), 65-87.

Yu, D., Blankert, B., VirÃ©, J-C. and Kauffmann, J-M., Biosensors in Drug Discovery Analysis, Anal. Letters., 2005 (38), 1687-1701.

Ding, C., Zhao, F., Zhang, M. and Zhang, S., Hybridization Biosensor Using 2,9-Dimethyl-1,10-Phenantroline Cobalt as Electrochemical Indicator for Detection of Hepatitis B Virus DNA, Bioelectrochemistry, 2008 (72), 28-33.

Arikyosal, D.O., Karadeniz, H., Erdem, A., Sengonul, A., Sayiner, A.A. and Ozsoz, M., Label-Free Electrochemical Hybridization Genosensor for the Detection of Hepatitis B Virus Genotype on the Development of Lamivudine Resistance, Anal. Chem., 2005 (77), 4908-4917.

Li, X-M., Ju, H-Q., Du, L-P. and Zhang, S-S., A Nucleic Acid Biosensor for the Detection of a Short Sequence Related to the Hepatitis B Virus Using Bis-(Benzimidazole)-Cadmium(II) Dinitrate as an Electrochemical Indicator, J. of Inorganic Chem., 2007 (101), 1165-1171.

Zhang, S., Tan, Q., Li, F. and Zhang, X., Hybridization Biosensor Using Diaquabis[N-(2-Pyridinylmethyl)Benzamide-Ðº2N,O]-Cadmium(II) Dinitrate as a New Electroactive Indicator for Detection of Human Hepatitis B Virus DNA, Sens. And Act. B: Chem., 2007 (124), 290-296.

Ionescu, R.E., Cosnier, S., Herzog, G., Gorgy, K., Leshem, B., Herrmann, S. and Marks, R.S., Enzyme Microb. Technol., 40 (2007), 403.

Lin, D., Tang, T., Jed Harrison, D., Lee W.E. and Jemere, A.B., A Regenerating Ultrasensitive Electrochemical Impedance Immunosensor for the Detection of Adenovirus, Biosens. Bioelectron., 2015 (68), 129-134.

Riccardi, C.S., Kowalik, J., Josowics, M., Hideko, Y., Mizaikoff, B. and Kranz, C., Label-Free DNA Detection of Hepatitis C Virus (HCV), 210th ECS Meeting, 2006, 585.

Liu, S., Hu, Y., Jin, J., Zhang H. and Cai, C., Electrochemical Detection of Hepatitis C Virus based on Site-Specific DNA Cleavage of BamHI Endonuclease, Chem. Commun., 2009 (13).

Wang, R., Xue, C., Gao, M., Qi, H. and Zhang, C., Ultratrace Voltammetric Method for the Detection of DNA Sequence Related to Human Immunodeficiency Virus Type 1, Microchim. Acta, 2011 (172), 291-297.

Tran, L.D., Nguyen, B.H., Van Hieu, N., Tran, H.V., Nguyen H. Le. and Nguyen, P.X., Electrochemical Detection of Short HIV Sequences on Chitosan/Fe 3O4 Nanoparticle Based Screen Printed Electrodes, Mater. Sci. Eng. C, 2011 (31), 477-485.

Chen, X., Xie, H., Seow, Z.Y. and Gao, Z., Biosensors and Bioelectronics an Ultrasensitive DNA Biosensor based on Enzyme-Catalyzed Deposition of Cupric Hexacyanoferrate Nanoparticles, Bioens. And Bioelectron., 2010 (25), 1420â€“6.

Zari, N., Amine, A. and Enhaji, M.M., Label-Free DNA Biosensor for Electrochemical Detection of Short DNA Sequences Related to Human Papilloma Virus, Anal. Letters, 2009 (42), 519-535.