ZingSweet: Herbal Drink Based on Ginger (Zingiber officinale Roscoe) and Licorice Root (Glycyrrhiza glabra L.) as an Anti-Inflammatory Agent and Throat Health Support

Abstract

Background: Synthetic drugs are often used to treat upper respiratory tract inflammation, including throat irritation, but they can cause side effects. Because they are more practical and safer, herbal plants are increasingly in demand. Ginger (Zingiber officinale Roscoe) contains shogaol and gingerol, which act as anti-inflammatories, antioxidants, and immunomodulators. Licorice root (Glycyrrhiza glabra L.) contains high levels of glycyrrhizin, which acts as an antimicrobial, expectorant, and throat mucosa protector. Objective: This study aims to evaluate the potential of combining ginger and licorice root in ZingSweet products as functional herbal drinks. Methods: This study used laboratory tests. Phytochemical screening tests were conducted using qualitative methods, in vitro anti-inflammatory tests using the red blood cell (RBC) membrane stabilization method, and organoleptic tests. Results: ZingSweet extract screening tests were positive for alkaloids, flavonoids, saponins, triterpenoids, and quinones, which act as anti-inflammatory and antioxidant agents. Anti-inflammatory testing showed very high membrane stabilization (99.22–99.34%) at concentrations of 5–80 ppm, close to the positive control (98.83%) and far above the negative control (0%). Organoleptic testing also showed that ZingSweet was preferred by panelists in terms of taste, color, and aroma. Conclusion: The combination of gingerol and glycyrrhizin in ZingSweet demonstrates strong anti-inflammatory effects, supports throat health, and is well-received organoleptically. With its instant sachet formulation, this product has the potential to be developed as a practical and safe functional herbal beverage.

Keywords: ginger, licorice root, anti-inflammatory, herbal drink, ZingSweet