SENSITIVITY TEST OF Methicillin-resistant Staphylococcus aureus BACTERIES TO ANTIBIOTICS

Abstract

Methicillin-resistant Staphylococcus aureus, an infectious disease caused by the Staphylococcus aureus bacteria, which has developed resistance to antibiotics. The spread of this infection is a new challenge for medical professionals due to the increased risk of morbidity and mortality that occurs. The study aimed to evaluate the sensitivity of Methicillin-resistant Staphylococcus aureus (MRSA) to various antibiotics, including gentamicin, ciprofloxacin, cefixime, vancomycin, and chloramphenicol. This descriptive research involved laboratory testing to determine antibiotic effectiveness.The results of laboratory tests showed that Methicillin-resistant Staphylococcus aureus bacteria exhibited sensitivity to ciprofloxacin antibiotics, showing an inhibition zone of 23.8 mm at a 5 mcg dose, Gentamicin antibiotics demonstrated an inhibition zone of 21.3 mm at a concentration of 10 mcg, while vancomycin antibiotics showed an inhibition zone of 18.5 mm at a concentration of 30 mcg. Methicillin-resistant Staphylococcus aureus (MRSA) was resistant to cefixime antibiotics at a concentration of 5 mcg and chloramphenicol antibiotics at a concentration of 30 mcg, showing an inhibition zone of 0 mm for both. Ciprofloxacin, gentamicin, and vancomycin antibiotics are suitable for use as antibiotics to treat Methicillin-resistant Staphylococus aureus infections, while chloramphenicol antibiotics and cefixme antibiotics are not suitable for use. Inappropriate use of antibiotics causes bacterial resistance to antibiotics and can be very fatal, therefore the use of antibiotics needs to be done wisely and rationally based on doctor's recommendations.

Kata kunci : Antibiotics, Methicillin Resistant Staphylococcus aureus