Jelita Tea: Herbal Drink Anti-Typhoid Fever From Pomelo’s Peel (Citrus maxima) and Stevia Leaf (Stevia rebaudiana)

Ni Made Deliabudi Apriliapatni, FNU Burhannuddin, Ni Made Harisna Laksmi Dirtayanti, Ida Ayu Candra Sawitri

Abstract


Typhoid fever is an acute systemic infection caused by Salmonella typhi with the prevalence of this disease in Indonesia reaches 1.6%. The commonly used treatment for typhoid fever is antibiotic chloramphenicol, but it causes aplastic anemia and inhibits the formation of blood cells. Alternative treatment is needed with the use nature ingredients such as of pomelo’s peel and stevia leaves. Pomelo has been known with the active ingredients content. The most active ingredients found in its peel, but has not been utilized enough. Stevia leaves are a natural sweetener that did not increase the blood sugar that can increase the bacterial virulence. The purpose of this study was to determine the effectiveness of Jelita (Jeruk Bali and Stevia) Tea as an anti-typhoid. Pre experimental study was conducted in vitro method by testing the effectiveness of Jelita extract to inhibit the Salmonella typhi. The experimental study was conducted in vivo method with posttest-only-control group design using 3 treatment groups and 2 groups of control. In vitro test results obtained a signification of 0.037 (p<0.05) showing a significant difference between inhibitory zone produced by the test solution and negative control. In vivo tests result analyzed statistical with the Mann-Whitney test showed a signification of 0.1000(p>0.05) means there is a significant difference in antibody titers between the control group and each group. So, the conclusion is Jelita tea has potential as an anti-typhoid fever.Keywords: Typhoid Fever, Pamelo’s Peel, Stevia Leaf, Widal Test 

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DOI: https://doi.org/10.33992/icmahs.v1i1.3033

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