STINGLESS BEE-DERIVED NATURAL COMPOUNDS AS ANTI-INFECTIVE AGENTS: COMPARATIVE GC-MS PROFILING OF Itama sp. AND Tetragonula laeviceps
DOI:
https://doi.org/10.33992/meditory.v13i1.3977Abstract
Background: Stingless bee honey is recognized for its therapeutic value, which is attributed to a diverse array of bioactive compounds.
Objective: Â This study aimed to compare the chemical profiles of honey from Tetragonula laeviceps and Itama sp. using gas chromatography-mass spectrometry (GC-MS), focusing on antimicrobial constituents.
Methods: Honey samples were collected from Bali, Indonesia, and analyzed using GC-MS. Compounds were identified through spectral matching with established libraries, and primary constituents were compared based on relative abundance.
Results:  T. laeviceps honey showed a high concentration of the rare sugar allose (7.6%), azulene (1.02%), and octadecanoic acid (2.07%), whereas Itama honey exhibited elevated levels of levoglucosan (5.35%), aromatic esters, and 3-methyl-2-furylacetone (2.58%). Notably, 5-hydroxymethylfurfural (HMF), known for its antimicrobial properties, was present in both samples at comparable levels (1–2%).
Conclusions: The metabolite variations between the two species reflect differences in foraging and resin collection behavior, influencing honey bioactivity. The unique profiles suggest that both types of honey possess valuable antimicrobial potential and could serve as sources for developing novel anti-infective agents.
Downloads
Published
Issue
Section
Citation Check
License
- Articles published in Meditory are licensed under a Creative Commons Attribution-ShareAlike 4.0 International license. You are free to copy, transform, or redistribute articles for any lawful purpose in any medium, provided you give appropriate credit to the original author(s) and Meditory, link to the license, indicate if changes were made, and redistribute any derivative work under the same license.
- Copyright on articles is retained by the respective author(s), without restrictions. A non-exclusive license is granted to Meditory to publish the article and identify itself as its original publisher, along with the commercial right to include the article in a hardcopy issue for sale to libraries and individuals.
- By publishing in Meditory, authors grant any third party the right to use their article to the extent provided by the Creative Commons Attribution-ShareAlike 4.0 International license.
