NILAI INDEKS TROMBOSIT SEBAGAI KONTROL KUALITAS KOMPONEN KONSENTRAT TROMBOSIT

Dewi Astuti

Abstract


Platelet component therapy is given to patients who have thrombocytopenia and platelet dysfunction, therefore an assessment of the quality of platelet components is necessary. The platelet component evaluation in UTDD PMI DKI Jakarta was carried out on the parameters of blood type test, volume, platelet count, pH and macroscopic examination of platelets (swirling) once on days 1, 2 or 3. This study aims to determine the value of the platelet index during the shelf life of the platelet concentrate component as a quality control. The research method uses a cross sectional experimental approach. Platelet index analysis was performed using Sysmex SN 350 hematology analyzer on five platelet component samples. The quality of platelet components is assessed based on the presence or absence of the difference between the platelet index values during the shelf life. Statistical results show that there are significant differences in the values of MPV, PDW and PCT from the shelf life of the 2nd day until the 5th day, but the examination results are still within normal limits. Platelet index results show an increasing trend. This indicates an increase in platelet volume and variations in platelet form. The conclusion of this study, the platelet component has good quality until the 5th day, and the platelet index value can be used as a platelet quality control parameter.


Keywords


: platelet component; the quality of platelet components; shelf life ; platelet index value

Full Text:

PDF

References


Budak YU, Polat M, Huysal K. The use of platelet indices, plateletcrit, mean platelet volume and platelet distribution width in emergency non-traumatic abdominal surgery: a systematic review. 2016;(3):178–93.

Bashir S, Mohsin S, Amin H, Rehman M, Hussain S, Saeed T. and without platelet additive solution. 2014;5(1):10–4.

Marpaung E, Setiawaty V, Ritchie NK, Timan IS. Function and platelet count in thrombocyte concentrate ( TC ) during the storage. 2016;(June 2015).

Kesehatan K. Peraturan Menteri Kesehatan Republik Indonesia No 91 Tahun 2015 tantang Standar Pelayanan Transfusi Darah. 2016th ed. Jakarta; 2016.

Bank AB, José M, Coêlho D. Platelet aggregation and quality control of platelet concentrates produced in the. 2011;

J Botma, LF Moongoa, AD Jaftha W janse van R. Reference ranges for platelet indices using sysmex XE-2100 blood analyser. 2012;

Chandra T, Gupta A, Kumar A, Afreen S. Morphological and functional changes in random donor platelets stored for seven days in platelet additive solution. Int J Blood Transfus Immunohematol. 2011;1:20.

Mohsin S, Rehman M, Saeed T, Amin H, Bashir S, Hussain S. Comparison of changes in platelet count, mean platelet volume and swirling in stored platelet concentrates with and without platelet additive solution. J Appl Hematol. 2014;5(1):10.

Vani C. Platelecrit as screening tool for detection of platelet quantitative disorders. J Hematol. 2013;2:22–6.

Wang F, Meng Z, Li S, Zhang Y, Wu H. Platelet Distribution Width Levels Can Be a Predictor in the Diagnosis of Persistent Organ Failure in Acute Pancreatitis. Gastroenterol Res Pract. 2017;2017.




DOI: https://doi.org/10.33992/m.v8i2.1238

Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Meditory

POLTEKKES KEMENKES DENPASAR
Address: Jl. Sanitasi No.1, Sidakarya, Denpasar Selatan, Kota Denpasar, Bali 80224 (0361) 710447