Doratea: Anti-Cancer Tea From Robusta Coffee Leaves (Coffea canephora L.) and Stevia Leaves (Stevia rebaudiana)

Ni Kadek Wid Cahya Paramita

Abstract



Cancer is an abnormal condition of cell growth that can affect various parts of the body. It is the second leading cause of death in the world with a total of 9.6 million deaths. Many therapies and measures are needed to treat this condition. Cancer treatment involves various methods, such as chemotherapy, radiotherapy and surgery, which are chosen based on the type and stage of cancer. Prevention with a healthy lifestyle is also important to reduce the risk of developing cancer. Doratea is a functional drink with antioxidant content that has the potential to slow the growth of cancer cells. Robusta coffee leaves and stevia leaves contain flavonoids, tannins, saponins, and phenols. This study aims to determine anticancer activity by testing antioxidant and cytotoxin levels with the BSLT (Brine Shrimp Lethality Test) method. Doratea produced from a combination of robusta coffee leaves and stevia leaves, has a %inhibition value of DPPH of 51.187% with a concentration of 5000ppm. As for cytotoxin testing using Artemia salina shrimp, the LC50 result is 945.22 mg/L which can be categorized as toxic.


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Bariyyah, Siti & Hanapi, Ahmad & Fasya, Ahmad & Abidin, Munirul. (2013). UJI AKTIVITAS ANTIOKSIDAN TERHADAP DPPH DAN IDENTIFIKASI GOLONGAN SENYAWA AKTIF EKSTRAK KASAR MIKROALGA Chlorella sp. HASIL KULTIVASI DALAM MEDIUM EKSTRAK TAUGE. ALCHEMY. 10.18860/al.v0i0.2890.

Afriani S., Idiawati N., Destiarti L., dan Arianie L. 2014. UJI AKTIVITAS ANTIOKSIDAN DAGING BUAH ASAM PAYA (Eleiodoxa conferta Burret) DENGAN METODE DPPH DAN TIOSIONAT. JKK, Volume 3(1), halaman 49-56

Anjani, G. et al., 2020. Bioactive components and antibacterial activity in Robusta coffee leaves (coffea canephora). International Journal of Pharmaceutical Research , 12(3), p. 1374.

Balatif, R., & Sukma, A. A. M. (2021). Memahami Kaitan Gaya Hidup dengan Kanker: Sebagai Langkah Awal Pencegahan Kanker. SCRIPTA SCORE Scientific Medical Journal, 3(1), 40-50.

Chusniasih, Dewi., dan Tutik. 2020. UJI TOKSISITAS DENGAN METODE BRINE SHRIMP LETHALITY TEST (BSLT) DAN IDENTIFIKASI KOMPONEN FITOKIMIA EKSTRAK ASETON KULIT BUAH KAKAO (Theobroma cacao L.). Analit: Analytical and Environmental Chemistry, Vol. 2(2), 192-201.

Fadhli, Haiyul & Sya'bani, Uswatun. (2019). UJI SITOTOKSIK EKSTRAK KULIT BATANG TUMBUHAN KANGKANG KATUP (Bauhinia semibifida Roxb) DENGAN METODE BRINE SHRIMP LETHALITY TEST (BSLT). 9. 141-145.

Longo VD, Fontana L. Calorie restriction and cancer prevention: metabolic and molecular mechanisms. Trends Pharmacol Sci. 2010 Feb;31(2):89-98. doi: 10.1016/j.tips.2009.11.004. Epub 2010 Jan 25. PMID: 20097433; PMCID: PMC2829867.

Nita, V., & Indrayani, N. (2020). Pendidikan Kesehatan Dalam Upaya Pencegahan Kanker Serviks Pada Wanita Usia Subur. DINAMISIA: Jurnal Pengabdian Kepada Masyarakat, 4(2), 306-310.

Prasetyo, Eko., Kharomah, Naelaz Zukhruf Wakhidatul., dan Rahayu, Titi Pudji. 2021. Uji Aktivitas Antioksidan Menggunakan Metode DPPH (2,2-difenil-1-pikrilhidrazil) Terhadap Ekstrak Etanol Kulit Buah Durian (Durio zibethinnus L.) dari Desa Alasmalang Kabupaten Banyumas. Jurnal Pharmascience, Vol. 08, No.01, hal: 75-82




DOI: https://doi.org/10.33992/icmahs.v2i1.3755

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