EFEKTIVITAS OBAT KUMUR EKSTRAK ETANOL DAUN BELUNTAS (Pluchea indica L. ) UNTUK MENGATASI HALITOSIS PADA REMAJA
Abstract
Known as bad breath, halitosis also called oral malodor is a bad breath that comes from air expelled by a person through the mouth. Halitosis is caused by local and systemic factors, but 90% of patients with halitosis due to local factors in the oral cavity, including at adolescents. The purpose of this study was to determine the effectiveness of mouthwashes of ethanol extract of leaves beluntas to overcome halitosis. This is an experimental research with completely randomized with pre-post control group design. Samples are adolescents junior high school students. Data were analyzed by Wilcoxon test, Results shown that there is a significance difference before and after rinsing in the groups and Friedman test shown that there is the significance difference between groups. The results of the study shown that mean average of mouth rinsing with ethanol extract of beluntas leaves with 12.5% in concentration is 0.167 ± 0.408, with p = 0.038 or p <0.05, rinsing with ethanol extract of beluntas leaves with 25% in concentration is 0.516 ± 0.408 , with p = 0.023 or p <0.05, mouth rinsing using chlorhexidine 0,12% shown that mean is 0.000 ± 0.000, with p = 0.020 or p <0.05. mouth rinsing using Base formula material shown that mean is 0,833 ± 0.408, with p = 0,157 or p> 0.05. Analyze differences between groups to know the efectiveness of mouthwash treatment with Friedman test shown that p value = 0.000 or p<0.05. The conclusion is rinsing with ethanol extract of beluntas leaves with 12.5% and 25% in concentration and chlorhexidine 0,12% can reduce halitosis significantly, but rinsing with base formula of mouthwash can not be overcome halitosis significantly. There are significant differences of effectiveness of mouthwash between groups to overcome halitosis.
Keywords: mouthwash, ethanol extract of beluntas leaves, halitosis, adolescent
Keywords
Full Text:
PDF INDONESIAReferences
Rosenberg, M. 2002. The Science of Bad Breath. Sci. Am. Apr.; 286 (4): 72-79
Clarck,B., Harasthy,V.I., Scientist Find Bug Responsible for Bad Breath. Article. (Serial Online), (cited, 2010, November 4) , Available from: http://ukreuters.com/artcle/idUKTON77980320080407
Shahani, M.N., Reddy, V.V.S. 2011. Comparison of Antimicrobial Substantivity of Root Canal Irrigants in Instrumented RootCanals up
to 72 Hours: An Invitro Study. Journal of Indian Soc. Pedod. Prev.
Dent. 29: 28-33
Suriawiria, U, 2000, Obat Mujarab dari Pekarangan Rumah.Jakarta: Papas Sinar Sinanti. p. 29
Dalimartha, S.1999, Atlas Tumbuhan Obat Indonesia,Jilid I. J
akarta:TrubusAgriwidya. p. 18-21
Nahak,M.M., Tedjasulaksana,R., dan Dharmawati, IG.G.A. 2007.Khasiat Ekstrak Daun Beluntas untuk Menurunkan Jumlah Bakteri pada Saliva. Interdental Jurnal Kedokteran gigi, Denpasar.
(3): 139-142
Sulistyaningsih, Rr. 2009. Potensi Daun Beluntas (Pluchea indica
Less) Sebagai Inhibitor Terhadap Pseudomonas aeruginosa Multi Resistant dan Methicilline Resistant staphylococcus aureus. Laporan
Penelitian Mandiri. Fakultas Farmasi Univ. Padjadjaran Bandung. p. 34-35
Nahak, M.M. 2012. Ekstrak Etanol Daun Beluntas (Pluchea indica. L.) dapat Menghambat Pertumbuhan Bakteri Streptococcus mutans. Laporan Disertasi. Program Pasca Sarjana Universitas Udayana, Denpasar.
Nahak, M.M., Tedjasulaksana, R., Sumerti, N.N., 2015. Efektivitas Ekstrak Etanol Daun Beluntas untuk Menurunkan Jumlah Koloni Streptococcus sp. Pada Plak Gigi. Jurnal Skala Husada,
Denpasar.12(1): 56-64
Frederer, W.T. 1977. Experimental Design Theory and Application.
rd Edition. New Delhi, Bombay Calcuta. Oxford and IBHPublishing.Co. p. 544
Pasaribu, S.P. 2009. Uji Bioaktivitas Metabolit Sekunder dari Daun Tumbuhan Babadotan (Ageratum conyzoides L.). Jurnal Kimia
Mulawarman. 6(2): 1-7
Arief. 2000. Ilmu Meracik Obat. Teori dan Praktek. Yogyakarta:
Gadjahmada University Press. p. 25
Sunyoto, D, 2012, Statistik Non Parametrik untuk Kesehatan.Yogyakarta:Nuha Medika
Islam, A.K., Ali, M.A., Sayeed, A., Salam, S.M., Islam, A., Rahman, M., Khan, G.R., Khatun, S. 2003. An Antimicrobial Terpenoid from Caesalpinia pulcerrima Swartz: Its Characterization, Antimcrobial and Cytotoxic Activities. Asian J Plant Sci. 2: 17-24
Prabuseenivasan, S., Jayakumar, M., Ignacimuthu, S. 2006. In vitro Antibacterial Activity of Some Plant Essential Oils. BMC Complement. Altern. Med. 6:39
Praptiwi, Chairul, Harapini, M. 2006. Uji Efektivitas Ekstrak Etanol Buah Makasar (Brucea javanica L.Merr.) terhadap Plasmodium berghei Secara in-vivo pada Mencit. Laporan Penelitian. Bidang Botani, Puslit Biologi-LIPI, Bogor. p. 1-6
John, A.J., Kanurakran, V.P., George, V. 2007. Antibacterial Activity of Neolitsea foliosa (Nees) Gamlbe var. caesia (Meisner). J.Essent.Oil. Res. 19:498-500
Hussain, A., Wahab, S., Zarin, I., Sarfaraj Hussain, M.D. 2010.
Antibacterial Activity of the Leaves of Cocconia indica (W. and A) Wof India. Advances in Biological Research. 4(5): 241-248
Mohamed, S.S.H., Hansi, P.D., Thirumurugan, K. 2010. Antimicrobial Activity and Phytochemical Analysis of Selected Indian Folk Medicinal Plants. International Journal of Pharma Sciences and Research (IJPSR). 1(10): 430-434
Rosenberg, M., Amit, A. 2009. Home Care and Treatment of Bad
Breath. Article. (Serial Online) (Cited 2011 Sept 11). Available from: http://Smellwell.com/treatment-of-bad-breath
Machado, T.B., Pinto, A.V., Pinto, M.C.F.R., Leal, I.C.R., Silva, M.G., Amaral, A.C.F., Kuster, R.M., Netto-dos Santoz, K.R. 2003. In vitro Activity of Brazilian Medicinal Plants, Naturally Occuring Naphtoquinones and Their Analogues Against Methicilline Resistant Staphyloccoccus aureus. International Journal of Antimicrobial Agents. 21: 279-284
Braga, L.C., Shupp, J.W., Cummings, C., Jett, M., Takahashi, J.A., Carmo, L.S., Chartone-Souza, E., Nasclmento, A.M.A. 2005. Pomegranate Extract Inhibits Staphylococcus aureus Growth and
Subsequent Enterotoxin Production. Journal of Ethnopharmacology. 96 : 335-339
Kuyyakanond, T., Quenel, L.B. 1992. The Mechanism of Action of
Chlorhexidine. FEMS Microbiol Lett. 79(1-3): 211-215
Mandel, I.D. 1994. Antimicrobial Mouth Rinses: Overview & Update. J Am Dent Assoc. 125(25): 2S -10S
Kolahi, J., Soolati, A. 2006. Rinsing with Chlorhexidine Gluconate Solution after Brushing and Flossing Teeth: a Systematic Review of
Effectiveness. Quintessence Int. 37(8): 605-12
DOI: https://doi.org/10.33992/jkg.v8i2.1489
Refbacks
- There are currently no refbacks.