SIFAT ANTIMIKROBA KOMBINASI SENYAWA KIMIA ANTARA EKSTRAK DAUN LIDAH BUAYA (Aloe vera L) DENGAN DAUN SIRIH (Piper bettle L) TERHADAP BAKTERI STREPTOCOCUS MUTANS PENYEBAB DENTAL PLAK

Abstract

Background: Plants that are medical and used for generations are aloe vera and betel leaf, which contain natural chemical and have antimicrobial and antiseptic properties.

Objective: The purpose of this study was to calculate the growth inhibition zone of Streptococcus mutans by using the interaction of aloe vera extract and betel leaf, with a concentration of 50%, 75%, 100%.

Method: This research was carried out at the Microbiology Laboratory of Udayana University using a pure experimental method of extracts of Aloe vera leaves and betel leaves with concentrations of 50%, 75%, 100%, seven repetitions, using Streptococcus mutans ATCC 35668, and isolation media for Mueller Hilton plus 5 % goat blood.

Results: The average inhibition zone diameter in the interaction groups of aloe vera extract and betel leaf in each group was statistically significant difference (p <0.05), where the inhibitory concentration with the highest 100% concentration was an average of 82.6 mm with very strong criteria.

Conclusion: The interaction of aloe vera leaf extract and betel leaf with a concentration of 100% has the highest inhibitory power of 82.6 mm, with very strong criteria.